The 32-player tournament will take place from November 9-17 at WV Active Aldersley in Wolverhampton, as Humphries bids to retain the coveted Eric Bristow Trophy in the West Midlands.
The 29-year-old will headline Group A, which also features three-time runner-up Wade, Grand Slam debutant Mansell and Austria’s World Cup finalist Rodriguez.
Humphries performed magnificently to take the title 12 months ago, and the world number one will begin his title defence against the returning Rodriguez on Saturday’s bumper opening day.
Saturday November 9
Afternoon Session (1300-1700 GMT)
Group Stage x8 – Groups B-C-D-H First Matches
Stephen Bunting v Wessel Nijman (H)
Josh Rock v Gian van Veen (H)
Dave Chisnall v Connor Scutt (D)
Danny Noppert v Beau Greaves (B)
Martin Schindler v Cameron Menzies (B)
Rob Cross v Leonard Gates (C)
Peter Wright v Martin Lukeman (C)
Ross Smith v Ritchie Edhouse (D)
Evening Session (1900-2300 GMT)
Group Stage x8 – Groups A-E-F-G First Matches
James Wade v Mickey Mansell (A)
Gary Anderson v Ryan Joyce (G)
Dimitri Van den Bergh v Lourence Ilagan (F)
Michael Smith v Mensur Suljovic (E)
Michael van Gerwen v Noa-Lynn van Leuven (G)
Luke Littler v Keane Barry (F)
Luke Humphries v Rowby-John Rodriguez (A)
Mike De Decker v Jermaine Wattimena (E)
Sunday November 10
Afternoon Session (1300 GMT)
Group Stage x8 - Groups B-C-D-H Second Matches
Saturday’s winning players in each group meet, and Saturday’s losing players in each group meet.
Evening Session (1900 GMT)
Group Stage x8 - Groups A-E-F-G Second Matches
Saturday’s winning players in each group meet, and Saturday’s losing players in each group meet.
Monday November 11 (1900 GMT)
Group Stage x8
Groups A-D Final Matches
Tuesday November 12 (1900 GMT)
Group Stage x8
Groups E-H Final Matches
Wednesday November 13 (1900 GMT)
4x Second Round
Thursday November 14 (1900 GMT)
4x Second Round
Friday November 15 (1900 GMT)
2x Quarter-Finals
Saturday November 16 (1900 GMT)
2x Quarter-Finals
Sunday November 17
Afternoon Session (1300 GMT)
Semi-Finals
Evening Session (1930 GMT - please note amended start time)
Final
Group A
(1) Luke Humphries
James Wade
Mickey Mansell
Rowby-John Rodriguez
Group B
(8) Danny Noppert
Martin Schindler
Cameron Menzies
Beau Greaves
Group C
(4) Rob Cross
Peter Wright
Martin Lukeman
Leonard Gates
Group D
(5) Dave Chisnall
Ross Smith
Ritchie Edhouse
Connor Scutt
Group E
(2) Michael Smith
Mike De Decker
Jermaine Wattimena
Mensur Suljovic
Group F
(7) Dimitri Van den Bergh
Luke Littler
Keane Barry
Lourence Ilagan
Group G
(3) Michael van Gerwen
Gary Anderson
Ryan Joyce
Noa-Lynn van Leuven
Group H
(6) Stephen Bunting
Josh Rock
Gian van Veen
Wessel Nijman